V současné době
je vedoucím Vědecké sekce Kliniky dětské hematologie/onkologie v Sheba Medical Center (Tel-Hashomer, Israel).
Stručný životopis
Po absolutoriu medicíny a službě v izraelské armádě pracoval nejdříve ve Výzkumném ústavu dětské onkologie při Nemocnici u sv. Anny ve Vídni, poté 7 let v National Cancer Institute v Bethesdě a dále 3 roky na John’s Hopkins Medical School v Baltimore. Po návratu do Israele se ujal vedení výzkumu na Klinice dětské hematologie/onkologie v Sheba Medical Center a také výuky na Sackler Medical School.
Významné ceny
které obdržel S. Izraeli:
| 1999 | NIH Fellows Award for Research Excellence |
| 2002 | Hannover Award for Leukemia and Lymphoma Research |
| 2002 | Excellence Research Award Israel Cancer Association |
| 2003 | Frontiers of Science and Engineering Scholar, American National Academy of Science |
| 2006 | Excellence Research Award Israel Cancer Association |
| 2006 | Owen Rennert’s Endowed Lecture in Pediatric Oncology, Georgetown University |
| 2006 |
TEVA Founders gramt for bio-medical research excellence |
Vybrané publikace
- Izraeli, S., T. Colaizzo-Anas, V.L. Bertness, K. Mani, P.D. Aplan, and I.R. Kirsch, Expression of the SIL gene is correlated with growth induction and cellular proliferation. Cell Growth Differ, 1997. 8(11): p. 1171–9.
- Izraeli, S., L.A. Lowe, V.L. Bertness, D.J. Good, D.W. Dorward, I.R. Kirsch, and M.R. Kuehn, The SIL gene is required for mouse embryonic axial development and left-right specification. Nature, 1999. 399(6737): p. 691–4.
- Izraeli, S., L.A. Lowe, V.L. Bertness, S. Campaner, H. Hahn, I.R. Kirsch, and M.R. Kuehn, Genetic evidence that Sil is required for the Sonic Hedgehog response pathway. Genesis, 2001. 31(2): p. 72–7.
- Rainis, L., D. Bercovich, S. Strehl, A. Teigler-Schlegel, B. Stark, J. Trka, N. Amariglio, A. Biondi, I. Muler, G. Rechavi, H. Kempski, O.A. Haas, and S. Izraeli, Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood, 2003. 102(3): p. 981–6.
- Einav, U., Y. Tabach, G. Getz, A. Yitzhaky, U. Ozbek, N. Amariglio, S. Izraeli, G. Rechavi, and E. Domany, Gene expression analysis reveals a strong signature of an interferon-induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer. Oncogene, 2005. 24(42): p. 6367–75.
- Rainis, L., T. Toki, J.E. Pimanda, E. Rosenthal, K. Machol, S. Strehl, B. Gottgens, E. Ito, and S. Izraeli, The Proto-Oncogene ERG in Megakaryoblastic Leukemias. Cancer Res, 2005. 65(17): p. 7596–7602.
- Hochman, E., S. Kinston, A. Harmelin, B. Gottgens, and S. Izraeli, The SCL 3' enhancer responds to Hedgehog signaling during hemangioblast specification. Exp Hematol, 2006. 34(12): p. 1643–50.
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Erez, A., A. Castiel, L. Trakhtenbrot, M. Perelman, E. Rosenthal, I. Goldstein, N. Stettner, A. Harmelin, H. Eldar-Finkelman, S. Campaner, I. Kirsch, and S. Izraeli, The SIL gene is essential for mitotic entry and survival of cancer cells. Cancer Res, 2007. 67(9): p. 4022–7.
Citační ohlas
Shai Izraeli má více než 800 citací a h-index 16.
