From Mitophagy to Neurocognitive Impairment

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11 April 2024

8.30—17.00

Vlastenecký sál, Karolinum (Ovocný trh 3, Praha 1)

registrace


Thursday 11 April 2024

8.30–9.00

Meeting check-in

9.00–9.15

Opening ceremony

Martin Vyhnálek, Evandro F. Fang, and Kateřina Veverová

Mitophagy in basic research

Chairing: Evandro F. Fang

9.15–10.00

Genetic dissection of mitophagic mechanisms in ageing and age-associated neurodegenerative disorders

Nektarios Tavernarakis

10.00–10.20

The application of multi-omics combined with wet lab techniques to explore novel mechanisms of AD

Sofie Lautrup

10.20–10.40

Novel mechanisms of neuronal loss in AD

Johannes Frank

10.40–11.00

Coffee break

Mitophagy and clinical point of view

Chairing: Nektarios Tavernarakis

11.00–11.30

Alteration of human CSF and serum-based mitophagy biomarkers in the continuum of Alzheimer’s disease and frontotemporal lobar degeneration

Kateřina Veverová, Martin Vyhnálek

11.30–12.00

The ‘5As’: ageing, Alzheimer’s disease, autophagy, AI, and an ‘A’ molecule in brain health and longevity

Evandro F. Fang

12.00–12.30

Health benefits of the mitophagy activator Urolithin A – From preclinical models to clinical studies

David D’Amico

12.30–13.45

Lunch

13.45–13.50

Alzheimer’s Foundation

Šárka Kovandová

Blood-based biomarkers in AD

Chairing: Kateřina Veverová

13.50–14.20

Using brain organoids to model Alzheimer’s disease in vitro

Dáša Bohačiaková

14.20–15.00

Plasma biomarkers of Alzheimer’s disease: state of the art and next steps toward clinical implementation

Giovanni Bellomo

15.00–15.30

Coffee break

Neurocognitive impairment in AD

Chairing: Martin Vyhnálek

15.30–15.50

Detecting early cognitive markers of Alzheimer’s disease: from subjective experience to objective memory testing

Hana Horáková

15.50–16.10

Spatial navigation in Alzheimer’s disease

Jan Laczó

16.10–16.30

Current and future treatment of Alzheimer’s disease

Jakub Hort

16.30–16.50

Mental and spiritual well being, the impact on brain maintenance

Kateřina Sheardová

16.50–17.00

Closing ceremony 

Martin Vyhnálek, Evandro F. Fang, and Kateřina Veverová

Created: 7. 3. 2024 / Modified: 13. 3. 2024 / Mgr. Petr Andreas, Ph.D.