Femtogram Electroanalytical Detection of Prostatic Specific Antigen by Brdicka Reaction.

Hynek D, Krizkova S, Krejcova L, Gumulec J, Ryvolova M, Cernei N, Masarik M, Adam V, Trnkova L, Stiborova M, Eckschlager T, Hubalek J, Kizek R. Int. J. Electrochem. Sci., 7 (2012) 1749–1766. IF: 3.729

Department of Paediatric Haematology and Oncology
 
Abstract
Prostatic-specific antigen is considered as the best marker for prostate cancer. In spite of such intensive research in the field of electrochemical detection of some by-products connected with concentration of PSA, electrochemical behaviour of PSA has not been studied yet. The aim of this study was to investigate electrochemical catalytic signals of PSA using differential pulse voltammetry Brdicka reaction. The catalytic signals were studied using adsorptive transfer stripping technique as well as directly in the electrochemical cell.
 
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Created: 1. 3. 2013 / Modified: 4. 1. 2019 / prof. MUDr. Radek Špíšek, Ph.D.